Most of the volume of a mature follicle is made up of the fluid-filled

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The antrum is a fluid-filled space that develops within the ovary as the follicle grows, and it comprises most of the volume of a mature follicle. The corona radiata is a layer of cells that surround the oocyte and is just outside of the zona pellucida. The cumulus oophorus is a group of cells that surround the oocyte and are connected to it by a stalk of granulosa cells. The zona pellucida is an acellular layer that surrounds the oocyte and forms a barrier to fertilization.

Most of the Volume of a Mature Follicle Is Made