Redness, swelling, heat, and pain are the four cardinal signs of inflammation. A fifth sign that is frequently added is

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Quizplus · Accepted Answer

Loss of function is frequently added as the fifth sign of inflammation because it occurs when inflammation affects the function of the affected tissue or organ. The other choices are not typically considered as signs of inflammation. Lethargy refers to a general feeling of tiredness or lack of energy and is not specific to inflammation. Phagocytosis refers to the process by which white blood cells engulf and digest microorganisms or other foreign substances, which is a cellular response to inflammation but not a sign of inflammation itself. Pus formation is a result of the inflammatory response, but it is not considered one of the cardinal signs.

Redness, Swelling, Heat, and Pain Are the Four Cardinal Signs