According to the activation-synthesis model of dreaming, the activation of brainstem areas, which in turn trigger brain areas involved in sensation, emotions, and memory, causes dreaming.

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The activation-synthesis model of dreaming proposes that random electrical activity in the brainstem triggers the brain areas involved in sensation, emotions, and memory, leading to the creation of dream experiences, which is considered to be a bottom-up process.

According to the Activation-Synthesis Model of Dreaming, the Activation of Brainstem