Specialized neurons in the hypothalamus actively produce hypocretins during the daytime to maintain a steady state of wakefulness.

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Specialized neurons in the hypothalamus, called hypocretin-producing neurons or orexin-producing neurons, actively produce hypocretins during the daytime to promote wakefulness and maintain a stable state of arousal. Dysfunction or loss of these neurons has been associated with sleep disorders such as narcolepsy.

Specialized Neurons in the Hypothalamus Actively Produce Hypocretins During the Daytime