According to the Focus on Neuroscience box "The Addicted Brain," what is the biological basis for drug tolerance?
A) The brain's dopamine system adapts to the high levels of dopamine produced by use of the addictive drug.
B) Addictive drugs gradually create new but abnormal neural pathways in the brain's limbic system.
C) As the brain adjusts to the addictive substance, the threshold to activate neurons in the brain's motor and sensory areas is greatly increased.
D) The brain counteracts the effects of the addictive drug by overproducing the neurotransmitter serotonin.

Question

Quizplus · Accepted Answer

Drug tolerance is a biological adaptation that occurs when the brain's dopamine system adjusts to the high levels of dopamine produced by use of the addictive drug. Over time, the brain becomes less responsive to the drug, and users must take increasingly larger doses to achieve the same effects.

According to the Focus on Neuroscience Box "The Addicted Brain