Lithium stabilizes the availability of glutamate within a narrow normal range, preventing both abnormally high and abnormally low levels of the neurotransmitter.

Question

Quizplus · Accepted Answer

Lithium has been shown to modulate the glutamate system in various ways, including reducing glutamate release and enhancing glutamate reuptake, which helps regulate the availability of glutamate within a normal range. This is thought to contribute to lithium's effectiveness in treating bipolar disorder, which has been associated with dysregulated glutamate signaling.

Lithium Stabilizes the Availability of Glutamate Within a Narrow Normal