The most consistent brain structure abnormality that researchers have found in people with schizophrenia is enlargement of the:

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Enlargement of the ventricles is the most consistent brain structure abnormality found in people with schizophrenia. The ventricles are fluid-filled spaces in the brain, and enlarged ventricles suggest that there is less brain tissue volume in the surrounding areas. This abnormality has been found in numerous studies and is thought to be related to the development of the disorder.

The Most Consistent Brain Structure Abnormality That Researchers Have Found