Which of the Following Is an Example of a Gene

Which of the following is an example of a gene having an opposite effect across cultures?

A) A gene variant has been shown to increase risks of heart disease in one culture,but another culture is characterized by much lower risks of heart disease.
B) A gene variant exists in one culture to decrease allergic reactions to pollen,while the same gene variant exists in another culture to increase allergic reactions to pollen.
C) Studies have shown that collectivism and individualism both have genetic causes.
D) People in one culture generally have one variant of a particular gene,while people in another culture generally have another variant of the same gene.
E) A gene variant exists in some people in one culture to increase seeking of social support,while the same gene variant exists in other people in that culture to decrease seeking of social support.