The Wife of a Patient Who Is Undergoing a Chest

The wife of a patient who is undergoing a chest wall biopsy for suspected metastatic lung cancer says, "It is so surprising that all the blood tests he had done at his annual physical four months ago didn't show anything." Which of the following responses by the nurse is best?

A) "That is too bad, since cancer is usually treatable if it is found early."
B) "That is so disappointing.Has your husband had a physical every year?"
C) "Perhaps they didn't do the right tests at that time.Did your husband have any tumor markers drawn?"
D) "I'm sure you must feel frustrated.There really is no lab work that is done to detect lung cancer."