A patient is suspected of having Addison's disease.Which challenge test would be most appropriate to give this patient to confirm this suspicion?
A)Corticotropin-releasing hormone (CRH)stimulation
B)Dexamethasone suppression (overnight)
C)Adrenocorticotropic hormone (ACTH)stimulation, rapid test
D)Metyrapone stimulation (overnight)

Question

Quizplus · Accepted Answer

In Addison's disease, the adrenal glands do not produce enough cortisol. ACTH stimulation test is used for the diagnosis of adrenal insufficiency. A rapid ACTH stimulation test can be used to evaluate the body's ability to produce cortisol in response to ACTH. In Addison's disease, there is a lack of response to ACTH stimulation, resulting in low cortisol levels. Therefore, option C is the most appropriate test to confirm Addison's disease.

A Patient Is Suspected of Having Addison's Disease