A sickle cell screen ordered for a 2-month-old based on a family history of sickle cell trait returns with a negative result.Which action by the nurse is most appropriate?
A)Discuss the importance of birth control to avoid exposing another child to the risk of this disorder.
B)Instruct the family in strategies to decrease the risk of sickle cell crisis for this infant.
C)Reassure the family that the infant will not develop sickle cell disease since the family history is for sickle cell trait.
D)Review the need for further evaluation to confirm this result.

Question

Quizplus · Accepted Answer

A negative sickle cell screen in a 2-month-old, especially with a family history of sickle cell trait, may not be conclusive. Hemoglobin F (fetal hemoglobin) is predominant in infants and can interfere with some sickle cell screening tests, potentially leading to false-negative results. Therefore, further evaluation is necessary to confirm the initial screening result.

A Sickle Cell Screen Ordered for a 2-Month-Old Based on a Family