A patient who is preparing to undergo a blood transfusion is suspected of having an immunoglobulin deficiency that could result in anaphylaxis when the blood is transfused.Which test would be most appropriate for confirming this suspicion?
A)Immunofixation electrophoresis (IFE)
B)Immunoglobulin E (IgE)
C)Immunoglobulin A (IgA)
D)Immunosuppressant cyclosporine

Question

Quizplus · Accepted Answer

The most appropriate test for confirming a suspicion of an immunoglobulin deficiency that could result in anaphylaxis during a blood transfusion is testing for Immunoglobulin A (IgA) deficiency. IgA deficiency is the most common immunoglobulin deficiency and can lead to severe allergic reactions when IgA is present in the transfused blood but absent or very low in the recipient.

A Patient Who Is Preparing to Undergo a Blood Transfusion