Results from a patient's genetic testing indicate mutations in the KRAS gene.This finding is most associated with which of the following?
A)A greater risk for thromboembolism
B)A specific medication used to treat colorectal cancer being rendered ineffective
C)A higher risk for developing breast cancer
D)An ability to identify patients with melanoma who might benefit from treatment with specific drugs

Question

Quizplus · Accepted Answer

Mutations in the KRAS gene are most commonly associated with resistance to certain medications used to treat colorectal cancer, as the KRAS protein is involved in a pathway that promotes cell division and growth. This mutation can limit the effectiveness of drugs that target this pathway, such as cetuximab and panitumumab.

Results from a Patient's Genetic Testing Indicate Mutations in the KRAS