Adult patients at high risk for infective endocarditis should be prescribed 2 grams of amoxicillin 30 to 60 minutes before procedures.Patients allergic to amoxicillin may take clindamycin,600 mg,30 to 60 minutes before procedures.

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Both statements are accurate according to guidelines for the prevention of infective endocarditis in patients at high risk. Amoxicillin is the preferred antibiotic for prophylaxis, and clindamycin is an alternative for those allergic to penicillin.

Adult Patients at High Risk for Infective Endocarditis Should Be