The drug chloroquine has been widely used to treat the human parasite malaria. Mutations in the malaria gene pfcrt confer resistance to chloroquine. In some countries, more than 90% of malaria parasites had the pfcrt resistance alleles. When these countries stopped using chloroquine, the frequency of the pfcrt resistance alleles rapidly declined. Provide an evolutionary explanation for the decline in pfcrt resistance alleles after chloroquine was discontinued.

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The Answer of The drug chloroquine has been widely used to treat the human parasite malaria. Mutations in the malaria gene pfcrt confer resistance to chloroquine. In some countries, more than 90% of malaria parasites had the pfcrt resistance alleles. When these countries stopped using chloroquine, the frequency of the pfcrt resistance alleles rapidly declined. Provide an evolutionary explanation for the decline in pfcrt resistance alleles after chloroquine was discontinued.

The Drug Chloroquine Has Been Widely Used to Treat the Human