A social worker who counsels Down syndrome teens asks a researcher what will happen to her clients in their forties and fifties. Which reply should this expert give?

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Individuals with Down syndrome are at a significantly higher risk of developing Alzheimer's disease, especially as they age into their forties and fifties. This is due to the presence of an extra copy of chromosome 21, which contains a gene that produces amyloid precursor protein, a key factor in the development of Alzheimer's disease.

A Social Worker Who Counsels Down Syndrome Teens Asks a Researcher