Under Which of Randy Nesse and George Williams' Evolutionary Explanations

Under which of Randy Nesse and George Williams' evolutionary explanations for disease does the antagonistic pleiotropy hypothesis for senescence fall?

A) Natural selection has not had time to catch up with environmental changes.
B) Natural selection lacks foresight; we are stuck with historically contingent relics of the past.
C) Natural selection favors reproductive success, even at the expense of vulnerability to disease.
D) Some disease symptoms, though unpleasant, are actually beneficial.