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Phenylephrine (PE, See the Structure Below) Is a Nasal Decongestant

Question 121

Multiple Choice

Phenylephrine (PE, see the structure below) is a nasal decongestant and is the active ingredient in Sudafed, which contains phenylephrine hydrochloride (PEHCl) . This conjugate acid of phenylephrine (PEH+) has a pKa = 5.5. At a physiological pH of 7.4. what is the ratio of concentrations, [PE]/[PEH+]? Phenylephrine (PE, see the structure below)  is a nasal decongestant and is the active ingredient in Sudafed, which contains phenylephrine hydrochloride (PEHCl) . This conjugate acid of phenylephrine (PEH<sup>+</sup>)  has a pK<sub>a </sub>= 5.5. At a physiological pH of 7.4. what is the ratio of concentrations, [PE]/[PEH<sup>+</sup>]?   A)  6.7 B)  0.01 C)  0.14 D)  79 E)  21


A) 6.7
B) 0.01
C) 0.14
D) 79
E) 21

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