The New Madrid Earthquake of 1811 and the Charleston Earthquake

The New Madrid earthquake of 1811 and the Charleston earthquake of 1883 are notable for which of the following reasons?

A) Were relatively large and occurred in the interior of a tectonic plate.
B) Resulted in a very large number of human deaths.
C) Were the only earthquakes to occur in the U.S. during those years.
D) Occurred prior to the development of modern seismographs.
E) Were the first earthquakes in the U.S. since Europeans came to the continent.