If you created a strain of bacteria that overexpressed protease inhibitors, and then infected this bacteria with phage λ, would you expect the phage to follow the lytic or lysogenic cycle?
A) Lytic
B) Lysogenic
C) The protease inhibitors would have no bearing on which life cycle is chosen.

Question

Quizplus · Accepted Answer

Protease inhibitors prevent degradation of proteins, including those involved in phage replication. This would make it more difficult for the lambda phage to enter the lytic cycle, as it relies on hijacking the host's replication machinery to make copies of itself. Therefore, the phage would be more likely to enter the lysogenic cycle in this scenario.

If You Created a Strain of Bacteria That Overexpressed Protease