What is the difference between the allosteric and torpedo models of eukaryotic transcriptional termination?
A) The allosteric model is that RNA pol II becomes destabilized after transcription of the poly A signal sequence while the torpedo model is that the polymerase is physically removed from the DNA
B) The torpedo model is that RNA pol II becomes destabilized after transcription of the poly A signal sequence while the allosteric model is that the polymerase is physically removed from the DNA
C) The allosteric model is that RNA pol II becomes destabilized after transcription of the stop codon sequence while the torpedo model is that the polymerase is physically removed from the DNA
D) The torpedo model is that RNA pol II becomes destabilized after transcription of the stop codon while the allosteric model is that the polymerase is physically removed from the DNA
E) The only difference between the two models is the proteins that are involved in removing the RNA pol II from the DNA

Question

Quizplus · Accepted Answer

The allosteric model suggests that RNA polymerase II (RNA pol II) becomes destabilized and releases from the DNA after transcribing the polyadenylation (poly A) signal sequence, leading to termination of transcription. In contrast, the torpedo model proposes that after the poly A signal is transcribed, an exonuclease degrades the newly synthesized RNA until it catches up to the RNA pol II, leading to its removal from the DNA.

What Is the Difference Between the Allosteric and Torpedo Models