Which of the following is NOT a reason for the high fidelity of DNA synthesis of DNA Pol III?
A) The hydrogen bonding between purines and pyrimidines is stable.
B) The DNA polymerase is unlikely to form bonds between nucleotides if they are mismatched.
C) The DNA polymerase has exonuclease functions.
D) The DNA polymerase has the ability to change the structure of the base in order to form the correct bond.

Question

Quizplus · Accepted Answer

DNA polymerase does not have the ability to change the structure of the base in order to form the correct bond. Its high fidelity is primarily due to its ability to prevent the formation of mismatches through proofreading (exonuclease) activity and stable hydrogen bonding between purines and pyrimidines.

Which of the Following Is NOT a Reason for the High