What is the function of DNA ligase?
A)Connects Okazaki fragments by sealing nicks in the sugar-phosphate backbone
B)Unwinds the double helix by breaking the hydrogen bonding between the two strands at the replication fork
C)Reduces the torsional strain that builds up ahead of the replication fork as a result of unwinding
D)Binds to oriC and causes a short
E)Prevents the formation of secondary structures within single-stranded DNA

Question

Quizplus · Accepted Answer

DNA ligase is an enzyme that is responsible for sealing nicks in the sugar-phosphate backbone of DNA molecules. During DNA replication, there are often small gaps in the newly synthesized strand that need to be joined together, and DNA ligase is responsible for catalyzing the formation of phosphodiester bonds between these fragments. In eukaryotes, DNA ligase plays a critical role in linking together the Okazaki fragments that are synthesized on the lagging strand of the replication fork.

What Is the Function of DNA Ligase