What is the process called by which genetic changes occur in tumors and allows them to become increasingly aggressive over time?

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Clonal evolution refers to the process by which genetic changes occur in tumor cells that allow them to become increasingly aggressive over time. These genetic changes can give rise to new subclones of tumor cells with distinct characteristics and behaviors, leading to the development of more advanced and difficult-to-treat cancers. This process is a major driver of tumor progression and is a key factor in the development of cancer resistance to treatment.

What Is the Process Called by Which Genetic Changes Occur