Mutations in proto-oncogenes are generally _____, whereas mutations in tumor-suppressor alleles are generally _____.

Question

Quizplus · Accepted Answer

Mutations in proto-oncogenes are dominant, meaning that the mutated form of the gene overpowers the normal form. In contrast, mutations in tumor-suppressor alleles are recessive, meaning that both copies of the gene need to be mutated for the cancer-promoting effect to occur.

Mutations in Proto-Oncogenes Are Generally _____, Whereas Mutations in Tumor-Suppressor