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Which of the Following Occurs in Familial Retinoblastoma

Question 58

Multiple Choice

Which of the following occurs in familial retinoblastoma?


A) There are two subsequent gametic mutations in Retinoblastoma (Rb) gene.
B) A single mutation in the Retinoblastoma (Rb) gene leads to the loss of heterozygosity.
C) Tumors develop only after exposure to ionizing radiation.
D) Changes in the cytoskeleton lead to mutations in the Retinoblastoma (Rb) gene.
E) Multiple gametic cells mutate all at once.

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