A human gene with a disease phenotype is going to be mapped by positional cloning.Which would be the MOST useful for this task?

Question

Quizplus · Accepted Answer

Data about the inheritance of SNP markers in families with the disease is the most useful for mapping a human gene with a disease phenotype by positional cloning. This is because it allows for the identification of the specific genetic markers that are associated with the disease, which can then be used to locate the gene of interest within the genome. Bacterial homologs, a restriction enzyme map, microarray data, and whole-genome shotgun clones may provide useful information in other contexts, but are less directly relevant for this particular task.

A Human Gene with a Disease Phenotype Is Going to Be