The lungfish Protopterus aethiopicus has a genome 38 times larger than that of humans.Most of the DNA in this species is noncoding repetitive DNA.What type of library would be more efficient to use if you wish to compare the expressed regions of genes in the lungfish to those in humans?

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A cDNA library would be more efficient as it contains only the expressed regions of genes, which would be the focus of the comparison between the lungfish and humans. Both PCR and genomic libraries would contain a lot of noncoding repetitive DNA, which would not serve the purpose of the comparison. Knockout and transgenic libraries would not be relevant for this type of comparison either.

The Lungfish Protopterus Aethiopicus Has a Genome 38 Times Larger