Which of the following statements about CpG islands is CORRECT?
A)CpG islands are commonly found at the 3'UTR regions.
B)The CpG island methylation is universal across both prokaryotes and eukaryotes.
C)Methylated CpG islands is associated with gene repression.
D)Transcriptionally active DNA has higher frequency of methylated CpG.
E)An association exists between DNA methylation at the CpG island and acetylation of histone via recruitment of acetylases.

Question

Quizplus · Accepted Answer

Methylated CpG islands are associated with gene repression. Methylation at the CpG island can prevent binding of transcription factors and recruit repressive proteins such as histone deacetylases, leading to a more compact and inactive chromatin structure.

Which of the Following Statements About CpG Islands Is CORRECT