In a group of 500 people, the frequency of genotype NN is 40%. Assuming both autosomal inheritance and that the population is in Hardy-Weinberg equilibrium, how many individuals would you expect to have the MN genotype?

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Quizplus · Accepted Answer

The frequency of the N allele is sqrt(0.4) = 0.632. The frequency of the M allele is 1 - 0.632 = 0.368. The frequency of the MN genotype is 2 * 0.632 * 0.368 = 0.464. The number of individuals with the MN genotype is 0.464 * 500 = 232.

In a Group of 500 People, the Frequency of Genotype