A GWAS tests for a strong association of genotype (using DNA markers)and phenotype in natural populations. Therefore, which of the following would be true of linkage disequilibrium?
A)There is a significant correlation between phenotype and genotype.
B)The P value is 0.05.
C)The lod score is negative.
D)There is evidence of inbreeding.
E)There is a deviation from Hardy-Weinberg equilibrium.

Question

A GWAS tests for a strong association of genotype (using DNA markers)and phenotype in natural populations. Therefore, which of the following would be true of linkage disequilibrium?
A)There is a significant correlation between phenotype and genotype.
B)The P value is > 0.05.
C)The lod score is negative.
D)There is evidence of inbreeding.
E)There is a deviation from Hardy-Weinberg equilibrium.

Quizplus · Accepted Answer

Linkage disequilibrium refers to the non-random association of alleles at different loci. A significant correlation between phenotype and genotype indicates that certain alleles are associated with the phenotype, which is what GWAS aims to detect.

A GWAS Tests for a Strong Association of Genotype (Using