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You Are Interested in Sequencing the Gene for Tangier Disease

Question 51

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You are interested in sequencing the gene for Tangier disease (OMIM 205404). The disorder is rare, so it is feasible to obtain only very few samples. The approximate chromosomal location of the gene is known. How would you set about deciding on a model organism to use to study this disease, and what would you do once you had decided? (An outline of your procedure after the organism is chosen will be sufficient).

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If the chromosomal location of the gene ...

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