Which of the following would make a human disorder-causing allele or gene easiest to locate?
A)a genomic library for the chromosome on which the gene is located
B)a cDNA library for the chromosome on which the gene is located
C)a group of 10 known candidate genes
D)a transposon known to segregate with the gene
E)a single patient with a chromosomal translocation associated with the gene

Question

Quizplus · Accepted Answer

A single patient with a chromosomal translocation associated with the gene would provide a clear starting point for mapping the location of the gene. By identifying the breakpoints of the translocation, researchers can determine which genes are physically interrupted or relocated, providing strong clues about the location and identity of the disease-causing gene.

Which of the Following Would Make a Human Disorder-Causing Allele