You want to design a repressor protein mutant. Which protein domain is the best target for preventing binding of the corepressor?
A)DNA-binding domain
B)allosteric domain
C)promoter domain
D)helix-turn-helix domain
E)activator binding site

Question

Quizplus · Accepted Answer

The allosteric domain is responsible for binding to the corepressor, so mutations targeting this domain can prevent binding and therefore prevent the repressor from functioning. The other domains listed are important for other aspects of repressor protein function, but not directly involved in binding to the corepressor.

You Want to Design a Repressor Protein Mutant