What is the sequence and polarity of the DNA strand complementary to the strand 5'AAATGTCCATGC 3'?
A)5'TTTACAGGTACG 3'
B)3' AAATGTCCATGC 5'
C)3' TTTACAGGTACG 5'
D)5'UUUACAGGUACG 3'
E)3' UUUACAGGUACG 5'

Question

Quizplus · Accepted Answer

To determine the complementary strand, we use base pairing rules: A (adenine) pairs with T (thymine) and C (cytosine) pairs with G (guanine). In the given DNA strand, we start from 5' end and move towards 3' end. The complementary nucleotides to the given strand will be T,A,A,T,C,A,G,G,T,A,C,G (using A-T and G-C base pairing). Hence, the complementary strand will be 3' TTTACAGGTACG 5'.

What Is the Sequence and Polarity of the DNA Strand