Sickle-cell anemia is caused by a change in the primary structure of a subunit of the hemoglobin protein.

Question

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Sickle-cell anemia is caused by a single nucleotide substitution that results in a change from glutamic acid to valine in one of the subunits of the hemoglobin protein. This change alters the physical properties of hemoglobin, causing it to stick together and form elongated, sickle-shaped red blood cells.

Sickle-Cell Anemia Is Caused by a Change in the Primary