What pharmacologically active amine is responsible for the signs and symptoms encountered in an allergic reaction?
A)histamine
B)epinephrine
C)diphenhydramine
D)phenylephrine
E)dopamine

Question

Quizplus · Accepted Answer

Histamine is the primary pharmacologically active amine responsible for the signs and symptoms encountered in an allergic reaction. It is released from mast cells and basophils and can cause a wide array of effects, including vasodilation, bronchoconstriction, and increased vascular permeability, leading to the classic symptoms of itching, redness, and swelling. Epinephrine, diphenhydramine, phenylephrine, and dopamine may be used in the treatment of an allergic reaction, but histamine is the primary mediator.

What Pharmacologically Active Amine Is Responsible for the Signs and Symptoms