The first detectable sign of HIV infection in the body is

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The first detectable sign of HIV infection in the body is the presence of HIV antibodies in the blood. This can be detected through a blood test. Symptoms such as weight loss, weakness, and diarrhea may come later in the course of HIV infection. The proliferation of macrophages and B-cells is part of the immune response to HIV, but it is not the first detectable sign of infection. The presence of HIV itself in the blood can also be detected through a blood test, but this generally occurs after the initial HIV antibodies have developed.

The First Detectable Sign of HIV Infection in the Body