A major limitation of present-day,long-term drug therapy for parkinsonism is:
A) a high incidence of serious liver toxicity associated with levodopa.
B) a rebound or withdrawal effect following discontinuation of treatment.
C) a sensitization phenomenon wherein less and less drug is needed even as dyskinesia and other side effects develop.
D) decreased effectiveness of levodopa.
Correct Answer:
Verified
Q28: Traditional drug treatments for parkinsonism target the
Q29: The enzyme _ converts dopa into
Q30: Selegiline ameliorates symptoms of parkinsonism through a
Q31: Carbidopa works by inhibiting the breakdown of
Q32: Tolcapone and entacapone,the two main COMT-inhibitory drugs:
A)inhibit
Q34: MAO-A is associated with _ neurons; MAO-B
Q35: The amount of levodopa that crosses the
Q36: The precursor of levodopa is:
A)dopamine.
B)dopa decarboxylase.
C)tyramine.
D)tyrosine.
Q37: All of the following treatments ameliorate parkinsonism
Q38: Levodopa therapy will typically be effective in
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