Cardiac toxicity is an effect most clearly associated with overdose of:

Question

Quizplus · Accepted Answer

Cardiac toxicity is most clearly associated with overdose of TCAs (tricyclic antidepressants). This is because TCAs can cause arrhythmias, decreased cardiac contractility, and decreased cardiac output, which can lead to cardiac arrest in severe cases. Overdose with SSRIs (selective serotonin reuptake inhibitors) and second-generation antidepressants is less likely to cause cardiac toxicity, although it may cause other symptoms such as gastrointestinal upset and neurological effects. MAOIs (monoamine oxidase inhibitors) are also associated with a risk of hypertensive crisis in the event of overdose or dietary interactions, but this is not a form of cardiac toxicity.

Cardiac Toxicity Is an Effect Most Clearly Associated with Overdose