Endocannabinoids appear to differ from typical neurotransmitters in that they:
A)bind to postsynaptic receptors.
B)are synthesized on demand.
C)cause presynaptic autoreceptors to run in reverse.
D)bind to heteroreceptors on the postsynaptic membrane.

Question

Quizplus · Accepted Answer

Endocannabinoids are synthesized on demand, meaning that they are not stored in vesicles like typical neurotransmitters. They are synthesized rapidly in response to increased intracellular Ca2+ levels and are then released from the postsynaptic neuron. This retrograde signaling then binds and activates CB1 receptors on the presynaptic neuron, which inhibits further release of neurotransmitters.

Endocannabinoids Appear to Differ from Typical Neurotransmitters in That They