For the oligoribonucleotide pACGUAC, the nucleotide at the:
A) 3' end has a phosphate at its 3' hydroxyl.
B) 3' end is a purine.
C) 5' end has a 5' hydroxyl.
D) 5' end has a phosphate on its 5' hydroxyl.
E) 5' end is a pyrimidine.

Question

Quizplus · Accepted Answer

The prefix "p" in front of the oligoribonucleotide name indicates that there is a phosphate group attached to the 5' carbon of the first nucleotide. Therefore, the 5' end of the oligoribonucleotide has a phosphate on its 5' hydroxyl, and the correct option is D. The nucleotide at the 3' end should have a hydroxyl group on its 3' carbon, not a phosphate group, so option A is incorrect. The identity of the nucleotide at the 3' and 5' ends (purine or pyrimidine) cannot be determined based on the name of the oligoribonucleotide, so options B and E are also incorrect. Option C is also incorrect because the 5' end has a phosphate, not a hydroxyl group.

For the Oligoribonucleotide PACGUAC, the Nucleotide at The