Which statement about intrinsically disordered proteins is TRUE?
A) They contain small hydrophobic cores.
B) They represent misfolded conformations of cellular proteins.
C) They have no stable three-dimensional structure and therefore have no cellular function.
D) They are responsible for proteostasis.
E) They can interact with multiple protein-binding partners and are central to protein interaction networks.

Question

Quizplus · Accepted Answer

Intrinsically disordered proteins (IDPs) have no stable three-dimensional structure and therefore can adopt different conformations in response to their binding partners. This unique property allows IDPs to interact with multiple protein-binding partners and participate in a wide range of biological processes, including signaling, transcriptional regulation, and cell cycle control. Hence, IDPs are central to protein interaction networks and play important roles in cellular function.

Which Statement About Intrinsically Disordered Proteins Is TRUE