Which method would be MOST useful to solve the atomic resolution structure of a protein that happens to easily form a repeating structure?
A) NMR
B) x-ray crystallography
C) mass spectrometry
D) circular dichroism
E) electron microscopy

Question

Quizplus · Accepted Answer

X-ray crystallography is the most commonly used method for solving atomic resolution structures of proteins. It requires the protein to form a crystalline structure, and proteins that form repeating units or have a high degree of internal symmetry are easier to crystallize. NMR may also be used to solve atomic resolution structures, but it is more challenging and time-consuming for larger proteins. Mass spectrometry and circular dichroism are useful for determining protein composition, but not for determining atomic resolution structures. Electron microscopy can be useful for determining the overall shape of large protein complexes, but it is not typically used for atomic resolution structure determination of individual proteins.

Which Method Would Be MOST Useful to Solve the Atomic