The functional differences, as well as differences in three-dimensional structures, between two different enzymes from E. coli result directly from their different:

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The amino acid sequences of enzymes determine their three-dimensional structures, as well as their functional differences. Differences in amino acid sequences can result in changes in the enzyme's active site, which may affect substrate specificity or catalytic efficiency. The other choices are not directly related to the differences between these enzymes.

The Functional Differences, as Well as Differences in Three-Dimensional Structures