Which Statement Does NOT Accurately Compare ER Signal Sequences and Nuclear

Which statement does NOT accurately compare ER signal sequences and nuclear localization sequences?

A) Nuclear localization sequences are not removed, while ER signal sequences usually are.
B) Nuclear localization sequences may be located anywhere, while signal sequences are usually found at the amino terminus.
C) Both nuclear localization sequences and signal sequences must contain multiple Asp and Glu residues.
D) Nuclear localization sequences and ER signal sequences are both sites for protein:protein interactions.
E) All these statements accurately describe these sequences.