After binding by E. coli RNA polymerase, the CORRECT order of events for transcription initiation is:
A) closed complex formation, open complex formation, promoter clearance, start of RNA synthesis.
B) closed complex formation, open complex formation, start of RNA synthesis, promoter clearance.
C) open complex formation, closed complex formation, start of RNA synthesis, promoter clearance.
D) start of RNA synthesis, closed complex formation, open complex formation, promoter clearance.
E) start of RNA synthesis, open complex formation, closed complex formation, promoter clearance.

Question

Quizplus · Accepted Answer

The correct order of events for transcription initiation by E. coli RNA polymerase is: closed complex formation (where the RNA polymerase binds to the promoter without causing the DNA strands to separate), open complex formation (where the DNA strands are separated to allow template strand access), start of RNA synthesis (where nucleotides are added to the growing RNA chain), and finally promoter clearance (where the RNA polymerase moves away from the promoter region to elongate the RNA transcript).

After Binding by E