E. coli RNA polymerase (RNAP) has no 3' to 5' exonuclease activity. Which statement BEST explains why this is not a required activity for this enzyme?
A) RNAP makes fewer errors in NTP addition, so this activity is unnecessary.
B) RNAP does not need to degrade nucleic acids ahead of the transcription bubble.
C) Errors in transcription will have no impact on the function of the RNA product.
D) Multiple RNA products are created and turnover rapidly, so errors have less impact.
E) None of the statements explains why this is not a required activity.

Question

Quizplus · Accepted Answer

RNA molecules are produced in large numbers and have a short lifespan, so errors in transcription are less detrimental compared to errors in DNA replication.

E Coli RNA Polymerase (RNAP) Has No 3' to 5