What do retrovirus reverse transcriptases use to initiate DNA synthesis?
A) They can synthesize DNA without a primer.
B) They require the action of cellular primase.
C) They contain a primase activity.
D) They use a tRNA molecule as a primer.
E) None of these is used by reverse transcriptases in initiation of DNA synthesis.

Question

Quizplus · Accepted Answer

Retrovirus reverse transcriptases use a tRNA molecule as a primer to initiate DNA synthesis. This tRNA is specifically bound to the viral RNA genome and serves as the starting point for the synthesis of the complementary DNA strand.

What Do Retrovirus Reverse Transcriptases Use to Initiate DNA Synthesis