AZT is one drug used as an HIV inhibitor. How does its structure differ from thymidine?
A) The aromatic ring in AZT is not methylated at the 5 position.
B) An azido group is present at C-2' in AZT.
C) An azido group is present at C-3' in AZT.
D) The 5' OH is methylated in AZT.
E) The aromatic ring is amidated at the 4 position.

Question

Quizplus · Accepted Answer

AZT (azidothymidine) has an azido group at the C-3 position of the thymidine molecule, which is absent in thymidine. The other options do not correctly describe the differences between AZT and thymidine.

AZT Is One Drug Used as an HIV Inhibitor